Nambarka kaska: 146-56-5 Qaaciddada Molecular: C20H21ClN2O4

Alaabta

Nambarka kaska: 146-56-5 Qaaciddada Molecular: C20H21ClN2O4

Sharaxaad Gaaban:

Lambarka Cas: 146-56-5
Magaca Kiimikada:
Foomka Unugyada Molecular: C20H21ClN2O4
La mid ah: chlorampridine


Faahfaahinta Alaabta

Tags Product

qeexida alaabta

Meesha dhalaalaysa 176-178°C
Cufnaanta 1.02 g/cm³
heerkulka kaydinta jeexjeexay heerkulka qolka, ka baxsan qorraxda tooska ah iyo jawi qoyan
milmayn 50 mg / ml (In ethanol);Aan biyo ku milmin
dhaqdhaqaaqa indhaha +111.6 darajo (C=1, methanol)
Muuqashada budo crystalline cad ama ku dhawaad ​​cad
daahirnimo ≥97%

daawooyinka farmashiyaha

waa "dihydropyridine calcium antagonist" (kalsiyum antagonist, ama kanaalka xannibaadda tartiib tartiib ah) kaas oo xannibaya dhaqdhaqaaqa "ion calcium" ee ku wajahan unugyada muruqyada siman ee xididdada dhiigga iyo myocytes wadnaha.Xogta tijaabadu waxay soo jeedinaysaa in la xidhiidha "goobaha xidhitaanka" ee "dihydropyridines" iyo "non-dihydropyridines".Labada muruqa wadnaha iyo xididdada dhiigga 'contractile' waxay ku xiran yihiin gelitaanka 'kaalshiyamka kaalshiyamka kalsiyumka' ee unugyadan iyada oo loo marayo kanaalada ion gaar ah.waxay si xushmad leh u joojisaa qulqulka ions calcium ee xuubabka unugyada, hab wax u dhimaya unugyada muruqyada siman ee xididdada dhiigga in ka badan unugyada wadnaha.Saamaynta inotropic (inotrope) taban, ama hoos u dhigista qanjidhada myocardial, ayaa lagu ogaan karaa gudaha vitro.Si kastaba ha ahaatee, saamaynta noocan oo kale ah laguma arag xayawaanka lagu maamulo qiyaasta daweynta ee loo qoray.Saamaynta kalsiyumka serum ma saameynayso .Marka la eego qiyaasta pH-ga jireed, waa unug ionised (pKa = 8.6) kaas oo isdhexgalka la leh kanaalka kaalshiyamka kaalshiyamka waxaa lagu gartaa heerka horumarsan ee isku-xirnaanta goobta soo-dhoweynta iyo kala-baxa, habkan heerka horumarka ah wuxuu keenaa saameyn bilow ah.

Isticmaalka iyo qiyaasta

waa Vasodilator arterial arterial kaas oo si toos ah ugu shaqeeya muruqa siman ee xididdada dhiigga, taasoo keentay hoos u dhac ku yimaada caabbinta xididdada xididada iyo hoos u dhaca cadaadiska dhiigga.Habka saxda ah ee lagu nafiso angina si buuxda looma fahmin, laakiin waxaa loo maleynayaa inay ku jiraan kuwan soo socda: angina Exertional: Bukaanka qaba angina firfircoon, NORVASC waxay yaraynaysaa wadarta caabbinta durugsan (ka dib markii la raro) inta lagu jiro shaqada wadnaha heer kasta oo jimicsi ah waxayna yaraynaysaa heerka badeecada cadaadiska, taas oo hoos u dhigaysa baahida ogsijiinta myocardial.

Ugu horrayn 5mg hal mar maalintii, taasoo kordhaysa ugu badnaan 10mg hal mar maalintii.

Cas Number 146-56-5

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