Rifampicin Cas lambarka: 13292-46-1 Qaaciddada Molecular: C43H58N4O12
| Meesha dhalaalaysa | 183 ° |
| Cufnaanta | 1.1782 |
| heerkulka kaydinta | 2-8°C |
| milmayn | chloroform: milmaya 50mg/ml, cad |
| dhaqdhaqaaqa indhaha | N/A |
| Muuqashada | casaan daciif ah ilaa casaan aad u madow |
| daahirnimo | ≥99% |
Rifampicin waa soosaar semisynthetic ah oo ka mid ah rifamicin B, antibiyootiko macrolactam ah iyo mid ka mid ah in ka badan shan antibiyootiko oo ka yimid isku dhafka rifamicin A, B, C, D, iyo E, kaas oo loo yaqaan Complex rifamicin, kaas oo ay soo saarto actinomycetes Streptomyces mediteranei ( Nocardia mediteranei).Waxaa lagu soo bandhigay dhaqanka caafimaadka 1968. Synthesis of rifampicin waxay ku bilaabataa xal aqueous ah ee rifamicin, kaas oo hoos yimaada xaaladaha falcelinta waa oksaydhed ilaa derivative cusub ee rifamicin S (32.7.4), oo leh dhex dhexaadinta rifamicin O (32.7. 3).Yaraynta qaab dhismeedka quinone ee alaabtan hydrogen iyadoo la isticmaalayo palladium ee kicinta kaarboon waxay siinaysaa rifamicin SV (32.7.5).Badeecada ka dhalata waxay martaa aminomethylation isku dar ah formaldehyde iyo pyrrolidine, taasoo siinaysa 3-pyrrolidinomethylrifamicin SV (32.7.6).Oxidsidaynta sheyga ka soo baxay oo leh tetracetate sunta rasaasta ah enamine iyo hydrolysis ku xiga oo leh xal aqueous ah ascorbic acid waxay siinaysaa 3-formylrifamicin SV (32.7.7).Ka falcelinta tan 1-amino-4-methylpiperazine waxay ku siinaysaa rifampicin la rabo (32.7.8).
Rifampin waxaa loo isticmaalaa sidii antibiyootik ahaan.Waa soosaar semisynthetic ah oo ka mid ah rifamycin B, oo ah antibiyootiko makrocyclic ah oo uu soo saaray caaryada Streptomyces mediterranei.Rifampin waxaa loo isticmaalaa daawaynta qaaxada, brucellosis, Staphlococcus aureus, iyo cudurrada kale ee faafa.
