Nambarka kaska: 224785-91-5 Formula Molecular: C23H33ClN6O4S
| Meesha dhalaalaysa | 214-216°C |
| Cufnaanta | N/A |
| heerkulka kaydinta | Jawi aan firfircoonayn, 2-8°C |
| milmayn | N/A |
| dhaqdhaqaaqa indhaha | N/A |
| Muuqashada | Cyrstalline-ka cad ilaa cad-cad |
| daahirnimo | ≥98% |
waxa uu ahaa wakiilka labaad ee suuqa la soo galiyay waxana uu faa’iido u lahaa in wakhtiga bilawga ah aan la dhimin iyada oo dawada caloosha buuxda laga qaatay .Waa 30 jeer ka xoog badan sida horjoogaha PDE5 (macnaha IC50, 3.9 nM) marka loo eego sildenafil iyo 10 jeer ka awood badan tadalafil, oo leh doorasho weyn (> 1,000 jeer) ee PDE5 bini'aadamka marka loo eego bini'aadamka PDE2, PDE3, iyo PDE4 iyo xulashada dhexdhexaadka ah (> 80 jeer) ee PDE1.Xulashada inhibitory PDE iyo labadaba in vitro iyo awoodda vivo ee horjoogaha cusub ee PDE5.waxay si gaar ah u joojisay hydrolysis of cGMP by PDE5, oo leh IC50 ee 0.7 nM (sildenafil 6.6 nM).IC50 ee PDE1 waxay ahayd 180 nM, PDE6 11 nM, iyo PDE2, PDE3 iyo PDE4 in ka badan 1,000 nM.
Xakameeyaha nooca 5 phsphodiesterase ee xulashada ah (PDE5).
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