Florfenicol Cas nambarka: 73231-34-2 Qaaciddada Molecular: C12H14Cl2FNO4S
2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1- (4-methylsulfonylphenyl) propan-2-yl] acetamide
AQUAFEN FLORFENICOL NUFLOR
[r- (r*, r*)] -n-[1- (fluoromethyl) -2-hydroxy-2- (4- (methylsulforyl) phenyl) -ethyl] -2,2-dichloroacetamide
[R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]ACETAMIDE
SCH-25298
(r- (r*,s*)) -methyleste
2,2-dichloro-n- (1- (fluoromethyl) -2-hydroxy-2- (4- (methylsulfonyl) phenyl) ethyl
4- (2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl) -benzenesulfonicaci
Florfeniol
FLUPROFEN
Fluorothiamphenicol
Sch-25298, Aquafen
Acetamide, 2,2-dichloro-N-(1S,2R)-1- (fluoromethyl) -2-hydroxy-2-4- (methylsulfonyl) phenylethyl-
2,2-Dichloro-N-[(1S,2R) -1- (fluoromethyl) -2-hydroxy-2-[4- (methylsulfonyl) phenyl] ethyl] acetamide
Aquaflor
Aquafen, Nuflor, SCH-25298, [R-(R*,S*)] -2,2-Dichloro-N-[1- (fluoromethyl) -2-hydroxy-2-[4- (methylsulfonyl) phenyl] ] acetamide
2,2-Dichloro-N- (1- (fluoromethyl) -2-hydroxy-2- (4- (methylsulfonyl) phenyl) ethyl) acetamide
2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1- (4-methylsulfonylphenyl) propan-2-yl] acetamid
| Meesha dhalaalaysa | 153 ° |
| Cufnaanta | 1.451± 0.06 g/cm3 (La saadaaliyay)1.1782 (qiyaas adag) |
| heerkulka kaydinta | 2-8°C |
| milmayn | Ku milmay ethanol ilaa 25mM iyo DMSO ilaa 100mM |
| dhaqdhaqaaqa indhaha | N/A |
| Muuqashada | Cadaan ilaa cad-cad |
| daahirnimo | ≥98% |
Florfenicol waa antibiyootiko fluorinated ah oo ballaadhan iyo ka soo jeeda thiamphenicol (Qaybta lambar 21357).Waxay ka hortagtaa go'doominta kiliinikada bini'aadamka ee bakteeriyada enteric, oo ay ku jiraan E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, iyo Salmonella (MIC)50s = 6.3-12.5 μg/ml).Florfenicol sidoo kale waxay ka firfircoon tahay go'doominta kiliinikada ee kala duwan ee cudurada neef-mareenka ee bovine iyo porcine, oo ay ku jiraan P. multocida, A. pleuropneumoniae, iyo B. bronchiseptica (MIC)50s = 0.25-4 μg/ml).Waxay joojisaa dhaqdhaqaaqa wareejinta peptidyl ee 70S ribosomes oo ka go'an E. coli marka la isticmaalo qiyaasta 1 mM.Daawooyinka ka kooban florfenicol ayaa loo isticmaalay daawaynta cudurada faafa ee neef-mareenka ee lo'da.
Waa nooc ka mid ah daawada bakteeriyada.Waxaa loo isticmaalaa sida dawooyinka ka hortagga jeermiska cudurada xoolaha ee lagu daweeyo cudurrada bakteeriyada ee doofaarka, digaagga iyo kalluunka.Waxay waxtar wanaagsan u leedahay daaweynta cudurrada caabuqa ee doofaarka, digaagga iyo kalluunka ay keento bakteeriyada xasaasiga ah, gaar ahaan daaweynta caabuqyada neef-mareenka iyo caabuqyada mindhicirka.
