Nambarka kaska: 54-31-9 Qaaciddada Molecular: C12H11ClN2O5S
| Meesha dhalaalaysa | 261-263°C |
| Cufnaanta | 1.16 (Qiyaas adag) |
| heerkulka kaydinta | Jawi aan firfircoonayn, heerkulka qolka 2-8°C |
| milmayn | DMSO:>5 mg/ml at 60°C |
| dhaqdhaqaaqa indhaha | N/A |
| Muuqashada | Off-White Solid |
| daahirnimo | ≥98% |
Telmisartan ayaa laga bilaabay Maraykanka si loogu daweeyo hypertension.Waxaa lagu diyaarin karaa siddeed tallaabo oo ka bilaabma methyl 4-amino-3-methyl benzoate;Wareegga koowaad iyo labaad ee giraanta benzimidazole waxay ku dhacdaa tallaabooyinka 4 iyo 6 siday u kala horreeyaan.Telmisartan waxay xannibaysaa ficilka angiotensin II (Ang II), molecule-ka asaasiga ah ee saameeya nidaamka renin-angiotensin-aldosterone (RAAS).Waa fasalka lixaad ee 《sartans》 in la suuq galiyo ka dib xarunta sunta rasaasta ee Losartan.Saameynteeda dheer (nolosha nuska 24) waxay noqon kartaa faraqa ugu weyn ee antagonistayaasha kale ee angiotensin II.Si ka duwan dhowr walax oo kale oo qaybtan ah, hawsheeda kuma xidhna marka loo beddelo dheef-shiid kiimikaad firfircoon, 1-O-acylglucuronide waa dheef-shiid kiimikaad ugu muhiimsan ee laga helo bini'aadamka.Telmisartan waa antagonist awood leh oo ka soo horjeeda AT1 reseptors kaas oo dhexdhexaadiya inta badan saameynta muhiimka ah ee angiotensin II iyada oo ay ka maqan tahay xiriirka AT2-hoosaadka ama daaweeyayaasha kale ee ku lug leh nidaaminta wadnaha.Dhowr daraasadood oo kiliinig ah, Telmisartan, hal mar qiyaasta maalinlaha ah, waxay soo saartey saameyn waxtar leh oo joogto ah hoos u dhigista cadaadiska dhiigga oo leh saameyn hoose oo saameynaya (gaar ahaan daawaynta la xiriirta qufaca oo la xidhiidha ACE inhibitors ee bukaanka waayeelka ah).
Telmisartan waa angiotensin II reseptor antagonist.
